Research teams and research areas

The Institut de la Vision brings together nearly 300 researchers in 18 research units specialized in ophthalmological pathologies. At the forefront of scientific innovation, these units conduct translational research aimed at developing cutting-edge technological solutions and therapeutic innovations for the prevention, diagnosis and treatment of these pathologies. Organized around five strategic research axes, the teams of the Institut de la Vision cover a wide range of topics, from the molecular physiology of vision to innovative therapeutic approaches.

Pathophysiology of the anterior segment of the eye

Our multidisciplinary team, comprising researchers, clinician-researchers, engineers, and students, is currently the only team in the Vision Institute working on the diseases of the anterior segment of the eye. Our preclinical and clinical research have focused on glaucoma, dry eye disease, ocular toxicology and ocular pain. 

Annabelle Réaux-Le Goazigo Principal Investigator
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Presentation

Our team is the only team in France and one of the few in the world to develop translational studies dedicated to ocular pain. Innovative fundamental and clinical research projects, conducted in collaboration with the Clinical Investigation Center and the Ophthalmobiology Laboratory at the Quinze-Vingts Hospital, aim to deepen our understanding of peripheral and central mechanisms associated with chronic dry eye disease and pain.

Our objective is to discover promising new therapeutic approaches aimed at alleviating pain in patients who currently lack effective treatments.
 

Research areas

  • Neuronal networks involved in chronic ocular pain

  • Neuroinflammation and ocular pain

  • Identification of new therapeutic targets for treating ocular pain

  • Identification of biomarkers in dry eye disease

  • Blue light and photophobia

  • Glaucoma: neuroinflammation and neuroprotection

Team members

Annabelle Réaux-Le Goazigo Principal Investigator
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Stéphane Melik-Parsadaniantz
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Christophe Baudouin
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William Rostene
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Antoine Labbe
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Françoise Baudouin
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Laurence Burgeais-Rambur
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Hong Liang
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Karima Kessal
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Elodie Reboussin
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Flora Morier
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Noémie Bonneau
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Tiffany Migeon
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Jiang Huang
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Juliette Buffault
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Zhang Jiayi
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Arnaud Cordovilla
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Scientific publications

Below you will find the latest scientific publications in this field: Pathophysiology of the anterior segment of the eye.

Transient Receptor Potential Channels: Important Players in Ocular Pain and Dry Eye Disease

Darine Fakih; Tiffany Migeon; Nathan MOREAU; Christophe Baudouin; Annabelle REAUX LE GOAZIGO; stephane melik parsadaniantz
Pharmaceutics 2022-09 | Journal article | Author DOI: 10.3390/pharmaceutics14091859

In vivo confocal microscopic study of corneal innervation in Sjögren's Syndrome with or without small fiber neuropathy.

Annabelle REAUX LE GOAZIGO
The ocular surface 2022-07-22 | Journal article DOI: 10.1016/j.jtos.2022.07.003 PMID: 35872076

Ultrasound localization microscopy and functional ultrasound imaging reveal atypical features of the trigeminal ganglion vasculature.

Annabelle REAUX LE GOAZIGO
Communications biology 2022-04-07 | Journal article DOI: 10.1038/s42003-022-03273-4 PMID: 35393515 PMC: PMC8989975

Corneal Nerve Abnormalities in Painful Dry Eye Disease Patients

Adrian Guerrero-Moreno; Hong Liang; Nathan Moreau; Jade Luzu; Ghislaine Rabut; Stéphane Melik Parsadaniantz; Antoine Labbé; Christophe Baudouin; Annabelle Réaux-Le Goazigo
Biomedicines 2021-10-09 | Journal article DOI: 10.3390/biomedicines9101424

Electrical match between initial segment and somatodendritic compartment for action potential backpropagation in retinal ganglion cells.

Annabelle REAUX LE GOAZIGO
Journal of neurophysiology 2021-05-26 | Journal article DOI: 10.1152/jn.00005.2021 PMID: 34038184

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