NeuroSensCol Biological Resource Centre

Presentation

The biological resources are extracted from patients who have neurosensory diseases, mainly retinal disorders, as well as control subjects (unaffected family members for monogenic diseases or examined controls for complex disorders).

The majority of blood samples are collected through the Center for Rare Diseases Referet of the hospital 15-20, a platform for precise retinal phenotyping. The NeuroSensCol CRB and the Center for Rare Diseases make sure of the ethical compliance for the safety of the subjects.

Since its creation in 2007, DNA is extracted from human peripheral blood with a salting-out precipitation method. The high quality of the DNA is ensured by a quality control testing.

The biological resources are stored in -80°C freezers, with 24-hour temperature monitoring. The DNA samples are included in various research projects at the Institut de la Vision, in university hospitals and research institutes in France and abroad. The high quality DNA is easily used for Sanger sequencing, Next Generation Sequencing (NGS), whole exome and whole genome sequencing as well as microarray analysis.

The BRC NeuroSensCol is certified ISO 9001.
The CRB NeuroSensCol is IBiSA certified.

The CRB NeuroSensCol is located at the platform of biological resources of the hospital Pitié-Salpêtrière. This platform is a clustering of independent Biological Resources Centers, in one building dedicated only for human biological resources conservation.