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Research / 9 October 2025

🎥 Co’Lab: when genetics and neurophysiology unveil the secrets of the retina

On the occasion of World Sight Day, the Institut de la Vision launches Co’Lab, a new video series where research comes together.
Each episode orchestrates the encounter between scientists from two different fields — genetics, neurophysiology, physics, imaging, engineering of technological platforms, and more. Together, they reveal how the synergy between their disciplines accelerates our understanding of visual mechanisms, sheds light on major questions in eye health, and paves the way for therapeutic innovations.

Photo portrait Olivier Marre et Christina Zeitz
Photo portrait Olivier Marre et Christina Zeitz

In this first episode, Christina Zeitz and Olivier Marre, both team leaders, explore the mechanisms of myopia, a major global public health issue.
Their approaches — one focused on genetic mechanisms, the other on retinal neurophysiology — converge to better understand how the eye regulates its growth and why, when it grows too much, it can endanger vision itself.

This synergy resonates particularly with two recent publications:
Olivier Marre and his collaborators have shown how the retina deciphers the quality of the image it receives and, through specialized cells, sends signals that slow down excessive eye growth. This discovery offers a new understanding of the mechanisms underlying myopia.
Read the article here

Christina Zeitz and her team have identified DUSP4 as a key gene involved in regulating myopia development, linking for the first time genetics, environmental factors (light), and retinal signaling within a single experimental model.
Read the article here

🎥 Dive into the cross-interview with Christina Zeitz and Olivier Marre in this first episode of Co’Lab.