The International AMD Genomics Consortium, which includes 26 centers worldwide, collected and analyzed the genetic data from 43,566 people of predominantly European ancestry to systematically identify common and rare variations in genetic coding — called variants — associated with AMD.

AMD is a progressive disease that causes the death of the retinal photoreceptors, the light-sensitive cells at the back of the eye. AMD is caused by a combination of genetic, environmental and lifestyle risk factors. Up to this point, researchers had identified 21 regions of the genome—called loci—that influence the risk of AMD. The new research, published in Nature Genetics, brings the number up to 34 loci.

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